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| 2. | | My history of (mostly failed) side projects and startups (gabrielweinberg.com) |
| 316 points by taylorwc on Oct 18, 2010 | 81 comments |
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| 3. | | Show HN: Hacker News, automagically organized (metaoptimize.com) |
| 274 points by bravura on Oct 18, 2010 | 36 comments |
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| 4. | | Ask PG: Lisp vs Python (2010) |
| 232 points by kung-fu-master on Oct 18, 2010 | 192 comments |
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| 5. | | Pilot Stands Up To TSA And Refuses Full Body Scan (expressjetpilots.com) |
| 188 points by yread on Oct 18, 2010 | 170 comments |
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| 6. | | Requiem For A Roommate (steveblank.com) |
| 185 points by aundumla on Oct 18, 2010 | 9 comments |
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| 7. | | HN-Books (hn-books.com) |
| 182 points by jacquesm on Oct 18, 2010 | 63 comments |
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| 8. | | Warren Buffett: Buying Berkshire Hathaway Was $200 Billion Blunder (yahoo.com) |
| 166 points by px on Oct 18, 2010 | 34 comments |
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| 9. | | Splendid Bacon: Simple Project Management for Hackers, built in 48 hours (splendidbacon.com) |
| 161 points by ljuti on Oct 18, 2010 | 115 comments |
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| 10. | | Ask Tom Preston-Werner, cofounder of GitHub, anything Today, Mon 18 Oct 2010. |
| 144 points by mojombo on Oct 18, 2010 | 139 comments |
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| 11. | | Apple Reports Fourth Quarter Results (apple.com) |
| 142 points by ugh on Oct 18, 2010 | 109 comments |
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| 12. | | Phusion Passenger 3.0.0 final released (phusion.nl) |
| 141 points by mickeyben on Oct 18, 2010 | 4 comments |
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| 13. | | Ray Ozzie leaving post as Microsoft's chief software architect (seattlepi.com) |
| 133 points by Flemlord on Oct 18, 2010 | 90 comments |
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| 14. | | How I Pitched TechCrunch And How To Get Press When You Launch Your Startup (jasonlbaptiste.com) |
| 136 points by jasonlbaptiste on Oct 18, 2010 | 26 comments |
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| 15. | | Facebook Apps transmit Personal IDs and Friends' Names to Advertisers (wsj.com) |
| 133 points by jakarta on Oct 18, 2010 | 27 comments |
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| 16. | | Programming is for Stupid People (whattofix.com) |
| 118 points by DanielBMarkham on Oct 18, 2010 | 67 comments |
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| 17. | | Is Microsoft in trouble? (fernstrategy.com) |
| 115 points by mjfern on Oct 18, 2010 | 85 comments |
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| 18. | | Bell System Technical Journal, 1922-1983 (bell-labs.com) |
| 112 points by ssclafani on Oct 18, 2010 | 20 comments |
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| 20. | | The Square Grid - New CSS-Grid (thesquaregrid.com) |
| 88 points by abp on Oct 18, 2010 | 31 comments |
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| 21. | | Desks Near Me - find great coworking places to work at (desksnear.me) |
| 88 points by pufuwozu on Oct 18, 2010 | 76 comments |
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| 23. | | Redis: under the hood (pauladamsmith.com) |
| 84 points by paulsmith on Oct 18, 2010 |
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| 24. | | Tldr.it - Summarizer for RSS feeds and other web pages (built in 48 hours) (tldr.it) |
| 85 points by jeremymcanally on Oct 18, 2010 | 43 comments |
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| 25. | | Redis, from the Ground Up (mjrusso.com) |
| 83 points by mjrusso on Oct 18, 2010 | 13 comments |
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| 29. | | Napping at work. A company that gets it. (transloc.com) |
| 79 points by aspirant on Oct 18, 2010 | 35 comments |
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| 30. | | Warn HN: When PayPal doesn't know the meaning of "Donation"... |
| 76 points by ComputerGuru on Oct 18, 2010 | 36 comments |
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I think Lisp still has an edge for larger projects and for applications where the speed of the compiled code is important. But Python has the edge (with a large number of students) when the main goal is communication, not programming per se.
In terms of programming-in-the-large, at Google and elsewhere, I think that language choice is not as important as all the other choices: if you have the right overall architecture, the right team of programmers, the right development process that allows for rapid development with continuous improvement, then many languages will work for you; if you don't have those things you're in trouble regardless of your language choice.