Yes, a lot. In fact, for the last 5-6 years I have been working to help develop and maintain a tool for VLSI chip design written in Common Lisp. (Unfortunately, the company that built it was recently acquired by a large publicly traded corporation, and they have decided to kill the project. Plus ca change, plus c'est la meme chose.)

I have also done a lot of personal coding in CL. Most recently I wrote a spam filter that I use in production on my personal mail server.