iOS development is not only objective-c and Cocoa Touch. XCode, interface builder, instruments are also big helpers and sometimes there can be memory problems that you can only trace with instrument.
Definitely. I know RubyMotion currently supports XIBs and Storyboards, but yeah there's no integrated solution with Xcode or Instruments right now. I personally like the Rake-based approach, its more lightweight than booting up an IDE, but I would bet that better Xcode support is possible since MacRuby already does it pretty well.
That's if you like using interface builder. I personally dislike it and prefer to lay things out programmatically, but this probably has to do with the fact that I came to iOS development from the web development world.
I also try to not use IB most of the time, but especially if you are building not so custom designs, IB really increase the productivity and keep the code clean.