I'm currently doing that for a project, but I'm about to change things up and use Babel anyways, for the following reasons:

- my project contains jsx files, which currently are compiled into .js files which feels a bit messy.

- I'm seriously considering using ES7's async/await functionality, which is not supported by node yet.

- and most importantly: node's ES6 support is incomplete. In particular, I miss default function parameters and destructuring assigment.

Using Babel would solve all these issues, and I could simply remove Babel once support is sufficient.