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It seems like giving half the people blackout curtains and then monitoring depression levels would be perfectly ethical, since it's expected to improve their life, if anything.


The problem with that is the placebo effect..


There are ways to set it up with an alternate/sham treatment for the control group (maybe some nice pictures to hang on the wall--something equally decorative but not light-blocking). It's not perfect because there's no way to make it fully blinded, but the results would still be a substantial improvement over the existing observational study discussed in the article here.


But the proposal was for a single-blind study in which half would have some other placebo, I take it.




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