* No support for files over 1GB (videos can easily go beyond that on modern cameras)
* Poor access times/latency for anything not on the current card (you have to manually swap it)
* You have to use tape
* Depending on the pricing, I'd be curious but my bet is that 1024 actually decent micro SD cards will cost at least 1$ a piece , and the 1TB uSD is only $449.99, so good luck finding that many cheap, and usable uSD cards.