I have no actual work experience prior to my current job and no degree. I am 23 years old and I have a 6 figure salary and equity in the Bay Area. If you know people that know what you are capable of and can refer you to a company then an amazing resume is completely irrelevant. Last week I turned down a job offer from Blizzard Entertainment (was by referral) because they could not match my current salary.
Luckily for us, we can prove it. Not many people will ever get a chance to say, "hey, let me show you that I can do it". There aren't many hobbyist surgeons (I hope).
Depends if you are actually good at something. Great engineers easily find work anywhere.
I am drop out. It took me only 1 week of looking to get a 6 figure job in the Bay Area with equity. It is also my first real job. It is nice knowing that I am in my early 20s with no college debt. College is great for networking though.
At least you're in good company: Steve Jobs, Bill Gates, and many others were dropouts too. Your challenge is to prove that you can stack up against someone with that piece of paper if it's a job you're looking for.