Settings like which version of Windows to impersonate, what TrueType fonts and DLLs need to be downloaded, what runtime to use (classic Wine or Proton), etc. can change from one application/game to another.
DOSBox also has similar front-ends that can start Doom with a Sound Blaster 16 but Duke Nukem with a Sound Canvas by applying different configuration files.
DOSBox also has similar front-ends that can start Doom with a Sound Blaster 16 but Duke Nukem with a Sound Canvas by applying different configuration files.