Qubes is cool, but Tails is for Tor and is meant to be a boot-from-live-cd or flash drive.
The whole point is that you want all instances of Tails to look the same on the network so they can't fingerprint you. Once you start making it a daily driver, picking up a lot of cookies, making it your own, etc. then the point of using it is moot.
[1] https://tails.net/
[2] https://www.qubes-os.org/
[3] https://www.youtube.com/watch?v=s8-B9d7iz1A