> The ribosome is an attractive antibiotic target because bacteria don’t easily develop resistance to drugs targeting the structure, adds Lewis.
Sure they do, by the general mechanism of preventing the drug from entering the bacterium and/or pumping it back out. Bacteria have general mechanisms for removing molecules they don't need.
This molecule is a peptide, so one mechanism for developing resistance would be evolution of a specific protease. Bacteria already have enzymes for breaking peptide bonds.
Sure they do, by the general mechanism of preventing the drug from entering the bacterium and/or pumping it back out. Bacteria have general mechanisms for removing molecules they don't need.
This molecule is a peptide, so one mechanism for developing resistance would be evolution of a specific protease. Bacteria already have enzymes for breaking peptide bonds.