Chrome and Firefox support WebTransport. Safari has announced intent to support it and they already use QUIC under the hood for HTTP/3.
Cloud services are pretty TCP/HTTP centric which can be annoying. Any provider that gives you UDP support can be used with QUIC, but you're in charge of certificates and load balancing.
QUIC is client->server so NATs are not a problem; 1 RTT to establish a connection. Iroh is an attempt at P2P QUIC using similar techniques to WebRTC but I don't think browser support will be a thing.
That is all sorts of miserable. I had an initial prototype that emulated UDP over SCTP, running QUIC (without encryption) on top. The problem is that SCTP becomes the bottleneck, plus it's super complicated.
I immediately jumped ship to WebTransport when Chrome added support. But I suppose there's no other option if you need P2P support in the browser.
Cloud services are pretty TCP/HTTP centric which can be annoying. Any provider that gives you UDP support can be used with QUIC, but you're in charge of certificates and load balancing.
QUIC is client->server so NATs are not a problem; 1 RTT to establish a connection. Iroh is an attempt at P2P QUIC using similar techniques to WebRTC but I don't think browser support will be a thing.